ALAS2 Antikörper (C-Term)

Produktnummer ABIN1449876

Der Kaninchen Polyklonal anti-ALAS2 Antikörper (ABIN1449876) detektiert spezifisch ALAS2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio) und Xenopus laevis.

Kurzübersicht für ALAS2 Antikörper (C-Term) (ABIN1449876)

Target: ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALAS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ALAS2 Antikörper

Bindungsspezifität: C-Term

Sequenz: VRLLKGEEGQ ALRRAHQRNV KHMRQLLMDR GLPVIPCPSH IIPIRVGNAA

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Bovine, African clawed frog, ZebrafishSpecies reactivity (tested):Human

Aufreinigung: Purified using peptide immunoaffinity column

Immunogen: Synthetic peptide directed towards the C terminal of human ALAS2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Details zu ALAS2

Target: ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))

Andere Bezeichnung: ALAS2

Hintergrund: ALAS2 specifies an erythroid-specific mitochondrially located enzyme. It catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia.The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.Synonyms: 5-aminolevulinate synthase erythroid-specific mitochondrial, 5-aminolevulinic acid synthase, ALASE, ASB, Delta-ALA synthetase, Delta-aminolevulinate synthase

Gen-ID: 212

NCBI Accession: NP_000023

Pathways: Transition Metal Ion Homeostasis