ALAS2 Antikörper (C-Term)

Produktnummer ABIN1449876

Dieses Anti-ALAS2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ALAS2 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio) und Xenopus laevis.

Kurzübersicht für ALAS2 Antikörper (C-Term) (ABIN1449876)

Target: ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALAS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ALAS2 Antikörper

Bindungsspezifität: C-Term

Sequenz: VRLLKGEEGQ ALRRAHQRNV KHMRQLLMDR GLPVIPCPSH IIPIRVGNAA

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Bovine, African clawed frog, ZebrafishSpecies reactivity (tested):Human

Aufreinigung: Purified using peptide immunoaffinity column

Immunogen: Synthetic peptide directed towards the C terminal of human ALAS2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Details zu ALAS2

Target: ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))

Andere Bezeichnung: ALAS2

Hintergrund: ALAS2 specifies an erythroid-specific mitochondrially located enzyme. It catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia.The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.Synonyms: 5-aminolevulinate synthase erythroid-specific mitochondrial, 5-aminolevulinic acid synthase, ALASE, ASB, Delta-ALA synthetase, Delta-aminolevulinate synthase

Gen-ID: 212

NCBI Accession: NP_000023

Pathways: Transition Metal Ion Homeostasis