ATG12 Antikörper (N-Term)
-
- Target Alle ATG12 Antikörper anzeigen
- ATG12 (Autophagy Related 12 (ATG12))
-
Bindungsspezifität
- AA 44-73, N-Term
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser ATG12 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody recognizes Human APG12L (N-term). Other species not tested.
- Aufreinigung
- Saturated Ammonium Sulfate precipitation followed by dialysis against PBS
- Immunogen
- KLH conjugated synthetic peptide between 44~73 amino acids from the N-term of Human APG12L Genename: ATG12
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product ATG12 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- Target
- ATG12 (Autophagy Related 12 (ATG12))
- Andere Bezeichnung
- ATG12 / APG12 (ATG12 Produkte)
- Hintergrund
- Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG12L is the human homolog of yeast APG12, a ubiquitin-activating enzyme E1-like protein essential for the conjugation system that mediates membrane fusion in autophagy.Synonyms: APG12-like, APG12L, Autophagy-related protein 12, Ubiquitin-like protein ATG12
- Molekulargewicht
- 15113 Da
- Gen-ID
- 9140
- NCBI Accession
- NP_004698
- Pathways
- Autophagie
-