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ATG12 Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ATG12 in WB, IHC (p) und EIA. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN1449610

Kurzübersicht für ATG12 Antikörper (N-Term) (ABIN1449610)

Target

Alle ATG12 Antikörper anzeigen
ATG12 (Autophagy Related 12 (ATG12))

Reaktivität

  • 73
  • 36
  • 26
  • 6
  • 6
  • 6
  • 6
  • 5
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Human

Wirt

  • 70
  • 19
  • 2
Kaninchen

Klonalität

  • 67
  • 24
Polyklonal

Konjugat

  • 50
  • 6
  • 5
  • 5
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ATG12 Antikörper ist unkonjugiert

Applikation

  • 68
  • 42
  • 30
  • 25
  • 16
  • 13
  • 13
  • 9
  • 9
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 15
    • 8
    • 8
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 44-73, N-Term

    Spezifität

    This antibody recognizes Human APG12L (N-term). Other species not tested.

    Aufreinigung

    Saturated Ammonium Sulfate precipitation followed by dialysis against PBS

    Immunogen

    KLH conjugated synthetic peptide between 44~73 amino acids from the N-term of Human APG12L Genename: ATG12

    Isotyp

    Ig Fraction
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.25 mg/mL

    Buffer

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    ATG12 (Autophagy Related 12 (ATG12))

    Andere Bezeichnung

    ATG12 / APG12

    Hintergrund

    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG12L is the human homolog of yeast APG12, a ubiquitin-activating enzyme E1-like protein essential for the conjugation system that mediates membrane fusion in autophagy.Synonyms: APG12-like, APG12L, Autophagy-related protein 12, Ubiquitin-like protein ATG12

    Molekulargewicht

    15113 Da

    Gen-ID

    9140

    NCBI Accession

    NP_004698

    Pathways

    Autophagie
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