SBDS Antikörper (N-Term)

Produktnummer ABIN1449399

Produktdetails anti-SBDS Antikörper

Target: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Bindungsspezifität: AA 1-250, N-Term

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SBDS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Protein-G affinity chromatography

Immunogen: Recombinant human SBDS (1-250aa) purified from E. coli

Klon: AT1E8

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Phosphate -Buffered Saline ( pH 7.4) with 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SBDS

Target: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Andere Bezeichnung: SBDS (SBDS Produkte)

Synonyme: cgi-97 antikoerper, sds antikoerper, swds antikoerper, zgc:56700 antikoerper, SDS antikoerper, SWDS antikoerper, 4733401P19Rik antikoerper, AI836084 antikoerper, CGI-97 antikoerper, SBDS ribosome assembly guanine nucleotide exchange factor antikoerper, hypothetical protein antikoerper, SBDS, ribosome maturation factor antikoerper, SBDS ribosome assembly guanine nucleotide exchange factor S homeolog antikoerper, SBDS ribosome maturation factor antikoerper, sbds antikoerper, LOAG_04440 antikoerper, sbds.S antikoerper, SBDS antikoerper, Sbds antikoerper

Hintergrund: The Shwachman-Bodian-Diamond syndrome (SBDS) is 249 amino acid ribosome maturation protein. The precise function of the SBDS protein is not known but it appears to play an important role in actin cytoskeletal function and mitotic spindle stabilization. Also, SBDS is required for the assembly of mature ribosomes and ribosome biogenesis. Mutations in the SBDS gene cause Shwachman-Diamond syndrome (SDS). SDS is an autosomal recessive disorder with clinical features that include pancreatic exocrine insufficiency, haematological dysfunction and skeletal abnormalities.Synonyms: Ribosome maturation protein SBDS, Shwachman-Bodian-Diamond syndrome protein

Gen-ID: 51119

NCBI Accession: NP_057122

UniProt: Q9Y3A5

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly