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NUMA1 Antikörper

NUMA1 Reaktivität: Human WB, IF, IP Wirt: Maus Monoclonal C02142 unconjugated
Produktnummer ABIN1449239
  • Target Alle NUMA1 Antikörper anzeigen
    NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
    Reaktivität
    • 83
    • 21
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 69
    • 14
    Maus
    Klonalität
    • 69
    • 14
    Monoklonal
    Konjugat
    • 37
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser NUMA1 Antikörper ist unkonjugiert
    Applikation
    • 30
    • 28
    • 26
    • 18
    • 18
    • 17
    • 14
    • 9
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    Spezifität
    This antibody reacts with human NuMA.
    Aufreinigung
    Protein A agarose
    Immunogen
    Protein fraction extracted from the mitotic chromosome
    Klon
    C02142
    Isotyp
    IgG1
    Top Product
    Discover our top product NUMA1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    Konservierungsmittel
    Without preservative
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Upon receipt, store (in aliqouts) at -20 °C.
  • Target
    NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
    Andere Bezeichnung
    NuMA (NUMA1 Produkte)
    Synonyme
    NUMA antikoerper, 6720401E04Rik antikoerper, AA764025 antikoerper, AL022610 antikoerper, AU014979 antikoerper, NUMA1 antikoerper, NuMA antikoerper, SP-H antikoerper, numa antikoerper, numa1 antikoerper, nuclear mitotic apparatus protein 1 antikoerper, nuclear mitotic apparatus protein 1 S homeolog antikoerper, NUMA1 antikoerper, Numa1 antikoerper, numa1 antikoerper, numa1.S antikoerper
    Hintergrund
    NuMA (Nuclear Mitotic Apparatus Protein) is involved in maintenance of nuclear structure and in the assembly of the mitotic spindle. During interphase, NuMA is present throughout the nucleus, and during mitosis, it localizes to the spindle. It associates with microtubule motors during mitosis, and plays an essential role in anchoring microtubule ends to the spindle poles. NuMA is an autoantigen, and some individuals with connective tissue disease or other autoimmune disorders have antibodies directed against the NuMA protein. Recent data suggests NuMA (240 kDa) is cleaved to a 180-200 kDa form during apoptosis.Synonyms: NUMA1, Nuclear mitotic apparatus protein 1, SP-H antigen
    Molekulargewicht
    240 kDa
    Gen-ID
    4926
    NCBI Accession
    NP_006176
    UniProt
    Q14980
    Pathways
    Caspase Kaskade in der Apoptose, Regulation of Actin Filament Polymerization, M Phase
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