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CYBA Antikörper (FITC)

CYBA Reaktivität: Human FACS Wirt: Maus Monoclonal 7D5 FITC
Produktnummer ABIN1449194
  • Target Alle CYBA Antikörper anzeigen
    CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))
    Reaktivität
    • 44
    • 19
    • 19
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 40
    • 4
    Maus
    Klonalität
    • 40
    • 4
    Monoklonal
    Konjugat
    • 15
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CYBA Antikörper ist konjugiert mit FITC
    Applikation
    • 35
    • 21
    • 17
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    This antibody reacts with an extracellular epitope of gp91phox. The antibody recognizes the epitope in the native conformation. This antibody reacts with Flavocytochrome b558 on flow cytometry.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human
    Aufreinigung
    Protein A agarose
    Immunogen
    Human cytochrome b rich fraction
    Klon
    7D5
    Isotyp
    IgG1
    Top Product
    Discover our top product CYBA Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    PBS, 0.09 % NaN3, 1 % BSA
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8 °C.
  • Target
    CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))
    Andere Bezeichnung
    Cytochrome B-245 Light Chain (CYBA Produkte)
    Synonyme
    zgc:66077 antikoerper, MGC80750 antikoerper, CYBA antikoerper, p22-phox antikoerper, p22phox antikoerper, p22-PHOX antikoerper, b558 antikoerper, nmf333 antikoerper, P22-PHOX antikoerper, cytochrome b-245, alpha polypeptide antikoerper, cytochrome b-245 alpha polypeptide L homeolog antikoerper, cytochrome b-245 alpha polypeptide antikoerper, cytochrome b-245 light chain-like antikoerper, cytochrome b-245 alpha chain antikoerper, p22-phox antikoerper, cyba antikoerper, cyba.L antikoerper, CYBA antikoerper, LOC101328418 antikoerper, Cyba antikoerper
    Hintergrund
    The NADPH oxidase is a multicomponent enzyme that transfers electrons from NADPH to O2 to generate superoxide (O2 -), a key part of the phagocytic or neutrophilic respiratory burst response. Flavocytochrome b558 is the catalytic component of the phagocyte NADPH oxidase. It is a transmembrane heterodimer composed of a large glycoprotein, gp91phox (PHagocyte OXidase) and a smaller protein, p22phox. Upon cell stimulation, flavocytochrome b558 assembles with p67phox, p47phox, and the GTP-binding protein Rac and becomes activated to generate O2 -. Mutations in gp91phox, p22phox, or other components of the NADPH oxidase can result in chronic granulomatous disease, which is associated with significant morbidity and mortality due to a predisposition to recurrent bacterial and fungal infections.Synonyms: CYBA, Cytochrome b(558) alpha chain, Cytochrome b558 subunit alpha, Neutrophil cytochrome b 22 kDa polypeptide, Superoxide-generating NADPH oxidase light chain subunit, p22 phagocyte B-cytochrome, p22-phox
    Gen-ID
    1535
    NCBI Accession
    NP_000092
    UniProt
    P13498
    Pathways
    Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
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