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- Target Alle CYBA Antikörper anzeigen
- CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CYBA Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- This antibody reacts with an extracellular epitope of gp91phox. The antibody recognizes the epitope in the native conformation or after treatment with guanidine or urea, but SDS treatment will abolish antibody binding.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human
- Aufreinigung
- Protein-A agarose
- Immunogen
- Human cytochrome b rich fraction
- Klon
- 7D5
- Isotyp
- IgG1
- Top Product
- Discover our top product CYBA Primärantikörper
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anti-Cytochrome B-245, alpha Polypeptide (CYBA) (AA 128-195) antibody
CYBA Reaktivität: Human ELISA, IF, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (AA 21-120) antibodyCYBA Reaktivität: Human, Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (AA 117-145), (C-Term) antibodyCYBA Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal RB31767 unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (N-Term) antibodyCYBA Reaktivität: Human, Maus, Ratte WB, ELISA, IF, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) antibodyCYBA Reaktivität: Human WB Wirt: Maus Monoclonal 44-1 unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) antibodyCYBA Reaktivität: Human WB, ELISA, IF, IHC (fro), FACS, ICC, IP Wirt: Maus Monoclonal CS9 unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (AA 107-156) antibodyCYBA Reaktivität: Human, Maus, Ratte, Hund, Pferd, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (Middle Region) antibodyCYBA Reaktivität: Human, Maus, Ratte, Schwein, Hund, Pferd, Rind (Kuh), Kaninchen, Schaf WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (AA 124-153), (C-Term) antibodyCYBA Reaktivität: Human WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS containing 50 % glycerol, pH 7.2
- Konservierungsmittel
- Azide free
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Upon receipt, store (in aliqouts) at -20 °C.
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- Target
- CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))
- Andere Bezeichnung
- Cytochrome B-245 Light Chain (CYBA Produkte)
- Hintergrund
- The NADPH oxidase is a multicomponent enzyme that transfers electrons from NADPH to O2 to generate superoxide (O2 -), a key part of the phagocytic or neutrophilic respiratory burst response. Flavocytochrome b558 is the catalytic component of the phagocyte NADPH oxidase. It is a transmembrane heterodimer composed of a large glycoprotein, gp91phox (PHagocyte OXidase) and a smaller protein, p22phox. Upon cell stimulation, flavocytochrome B558 assembles with p67phox, p47phox, and the GTP-binding protein Rac and becomes activated to generate O2 -. Mutations in gp91phox, p22phox, or other components of the NADPH oxidase can result in chronic granulomatous disease, which is associated with significant morbidity and mortality due to a predisposition to recurrent bacterial and fungal infections.Synonyms: CYBA, Cytochrome b(558) alpha chain, Cytochrome b558 subunit alpha, Neutrophil cytochrome b 22 kDa polypeptide, Superoxide-generating NADPH oxidase light chain subunit, p22 phagocyte B-cytochrome, p22-phox
- Gen-ID
- 1535
- NCBI Accession
- NP_000092
- UniProt
- P13498
- Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
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