MFGE8 Antikörper
Kurzübersicht für MFGE8 Antikörper (ABIN1449192)
Target
Alle MFGE8 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- This antibody reacts with MFG-E8 short and long form.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Mouse
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Aufreinigung
- Protein A agarose
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Immunogen
- Thioglycollate-elicited mouse peritoneal macrophages
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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Konservierungsmittel
- Without preservative
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Upon receipt, store (in aliqouts) at -20 °C.
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- MFGE8 (Milk Fat Globule-EGF Factor 8 Protein (MFGE8))
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Andere Bezeichnung
- Lactadherin
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Hintergrund
- Apoptotic cells are rapidly removed by phagocytosis to clear the living cells and tissues of intracellular materials being released from dying cells. Phagocytes recognize apoptotic cells through milk fat globule-EGF-factor 8 (MFG-E8). MFG-E8 is a secreted glycoprotein from thioglycollate-elicited macrophages and bind to phosphatidylserine exposed on the cell surface of apoptotic cells, then bind strongly to cells expressing ανβ3 integrin via its RGD (arginine-glycine-aspartate) motif. Thus, MFG-E8 is an important protein to mediate the engulfment of apoptotic cells by activated macrophages.Synonyms: Breast epithelial antigen BA46, HMFG, MFGE8, MFGM, Milk fat globule-EGF factor 8
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Gen-ID
- 4240
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NCBI Accession
- NP_001108086
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UniProt
- Q08431
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Pathways
- SARS-CoV-2 Protein Interaktom
Target
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