ABI1 Antikörper

Produktnummer ABIN1449186

Dieses Anti-ABI1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von ABI1 in WB, IP und IHC (p). Geeignet für Human, Maus und Hamster.

Kurzübersicht für ABI1 Antikörper (ABIN1449186)

Target: ABI1 (Abl-Interactor 1 (ABI1))

Reaktivität: Human, Maus, Hamster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ABI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 1B9

Produktdetails anti-ABI1 Antikörper

Spezifität: This antibody reacts with Abi-1.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse, Hamster

Aufreinigung: Protein A agarose

Immunogen: Human recombinant Abi-1 expressed in E. coli

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Upon receipt, store (in aliqouts) at -20 °C.

Details zu ABI1

Target: ABI1 (Abl-Interactor 1 (ABI1))

Andere Bezeichnung: ABI1 / SSH3BP1

Hintergrund: Abl interactor (Abi) proteins are c-Abl-binding proteins that bind to both the Src homology 3 (SH3) domain and the C-terminal proline-rich regions of Abl kinase through dual SH3-PXXP interactions. Two highly related genes, abi-1 and abi-2, were cloned. In addition to the interaction with Abl kinase, Abi proteins also interact with other signaling molecules. Recently, it has been reported that Abi-1 dramatically promoted c-Abl-mediated tyrosine (Tyr296) phosphorylation of Mena [mammalian homologue of Drosophila Enabled (Ena)] by interacting with both proteins.Synonyms: Abelson interactor 1, Abi-1, Abl interactor 1, Abl-binding protein 4, AblBP4, Eps8 SH3 domain-binding protein, Nap1-binding protein, Spectrin SH3 domain-binding protein 1, Spectrin binding protein, e3B1

Molekulargewicht: 65 kDa

Gen-ID: 10006

NCBI Accession: NP_001012768

UniProt: Q8IZP0

Pathways: RTK Signalweg, Response to Water Deprivation, ER-Nucleus Signaling