RNF2 Antikörper
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- Target Alle RNF2 Antikörper anzeigen
- RNF2 (Ring Finger Protein 2 (RNF2))
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Reaktivität
- Human, Maus, Hamster
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser RNF2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP)
- Spezifität
- This antibody reacts with Ring1B.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, Mouse, Hamster
- Aufreinigung
- Protein-A Sepharose
- Immunogen
- GST fusion mouse full-length Ring1B protein
- Klon
- 03-03-14
- Isotyp
- IgG2b
- Top Product
- Discover our top product RNF2 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
- Konservierungsmittel
- Without preservative
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- RNF2 (Ring Finger Protein 2 (RNF2))
- Andere Bezeichnung
- RNF2 (RNF2 Produkte)
- Synonyme
- BAP-1 antikoerper, BAP1 antikoerper, DING antikoerper, HIPI3 antikoerper, RING1B antikoerper, RING2 antikoerper, AI326319 antikoerper, AI450156 antikoerper, AU019207 antikoerper, Ring1B antikoerper, dinG antikoerper, fa19h05 antikoerper, ring1b antikoerper, wu:fa19h05 antikoerper, wz4556 antikoerper, bap-1 antikoerper, bap1 antikoerper, ding antikoerper, hipi3 antikoerper, ring2 antikoerper, ring finger protein 2 antikoerper, ring finger protein 2 L homeolog antikoerper, RNF2 antikoerper, Rnf2 antikoerper, rnf2 antikoerper, rnf2.L antikoerper
- Hintergrund
- Polycomb-group (PcG) proteins form multimeric complexes that maintain the state of transcriptional repression of several regulatory genes during development. Ring1B/Rnf2 forms part of a protein complex containing other PcG proteins, such as Mel18, Bmi1, MBLR, MPc3, and the spliceosome protein Sap155, and these complexes associate with chromatin to regulate transcription. Ring1B may also play a role in the regulation of Hox gene expression by PcG complexes. Deletion of Ring1B activity results in gastrulation arrest and cell cycle inhibition.Synonyms: BAP-1, BAP1, DING, E3 ubiquitin-protein ligase RING2, HIP2-interacting protein 3, HIPI3, Protein DinG, RING finger protein 2, RING1B
- Gen-ID
- 6045
- NCBI Accession
- NP_009143
- UniProt
- Q99496
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