RNF2 Antikörper

Produktnummer ABIN1449179

Der Maus Monoklonal Anti-RNF2-Antikörper wurde für WB und IP validiert. Er ist geeignet, RNF2 in Proben von Human, Maus und Hamster zu detektieren.

Kurzübersicht für RNF2 Antikörper (ABIN1449179)

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Reaktivität: Human, Maus, Hamster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RNF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Klon: 03-03-14

Produktdetails anti-RNF2 Antikörper

Spezifität: This antibody reacts with Ring1B.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse, Hamster

Aufreinigung: Protein-A Sepharose

Immunogen: GST fusion mouse full-length Ring1B protein

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu RNF2

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Andere Bezeichnung: RNF2

Hintergrund: Polycomb-group (PcG) proteins form multimeric complexes that maintain the state of transcriptional repression of several regulatory genes during development. Ring1B/Rnf2 forms part of a protein complex containing other PcG proteins, such as Mel18, Bmi1, MBLR, MPc3, and the spliceosome protein Sap155, and these complexes associate with chromatin to regulate transcription. Ring1B may also play a role in the regulation of Hox gene expression by PcG complexes. Deletion of Ring1B activity results in gastrulation arrest and cell cycle inhibition.Synonyms: BAP-1, BAP1, DING, E3 ubiquitin-protein ligase RING2, HIP2-interacting protein 3, HIPI3, Protein DinG, RING finger protein 2, RING1B

Gen-ID: 6045

NCBI Accession: NP_009143

UniProt: Q99496