RAB27A Antikörper (C-Term)

Produktnummer ABIN1440000

Zitiert in 3+ Publikationen. Der Ziege Polyklonal anti-RAB27A Antikörper (ABIN1440000) detektiert spezifisch RAB27A in WB, IF, IHC (p) und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Ziege, Pferd, Schaf, Hund, Meerschweinchen, Kaninchen, Affe, Huhn, Schwein, Cat, Esel, Hamster und Avian.

Kurzübersicht für RAB27A Antikörper (C-Term) (ABIN1440000)

Target: RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Ziege, Pferd, Schaf, Hund, Meerschweinchen, Kaninchen, Affe, Huhn, Schwein, Cat, Esel, Hamster, Avian

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser RAB27A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-RAB27A Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Anti-Rab27a

Sequenz: MHAYCENPDI VLCGNKSDLE DQRAVKEEEA RELAEKYGIP YFETSAANGT NISQAIEMLL DLIMKRMERC VDKSWIPEGV VRSNGHTSTD QLSEEKEKGL CGC

Spezifität: Detects Rab27a by Western blot in the following human, rat and mouse whole cell lysates and transfected cells with GFP-Rab27a. This antibody also recognizes Rab27b protein.

Produktmerkmale: RAB27A, member RAS oncogene family

Aufreinigung: Epitope affinity purified

Immunogen: Purified recombinant peptide derived from within residues 120 aa to the C-terminus of mouse Rab27a produced in E. coli.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:250-1:2,000, IF:1:50-1:200, IHC-P:1:50-1:400, IHC-F:1:50-1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: The antibody solution should be gently mixed before use.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Referenzen für anti-RAB27A Antikörper (ABIN1440000)

Alzahofi, Welz, Robinson, Page, Briggs, Stainthorp, Reekes, Elbe, Straub, Kallemeijn, Tate, Goff, Sviderskaya, Cantero, Montoliu, Nedelec, Miles, Bailly, Kerkhoff, Hume: "Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins." in: Nature communications, Vol. 11, Issue 1, pp. 3495, (2020) (PubMed).

Pelkonen, Reinisalo, Morin-Picardat, Kidron, Urtti: "Isolation of Intact and Functional Melanosomes from the Retinal Pigment Epithelium." in: PLoS ONE, Vol. 11, Issue 8, pp. e0160352, (2017) (PubMed).

Reichhart, Markowski, Ishiyama, Wagner, Crespo-Garcia, Schorb, Ramalho, Milenkovic, Föckler, Seabra, Strauß: "Rab27a GTPase modulates L-type Ca2+ channel function via interaction with the II-III linker of CaV1.3 subunit." in: Cellular signalling, Vol. 27, Issue 11, pp. 2231-40, (2016) (PubMed).

Details zu RAB27A

Target: RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

Andere Bezeichnung: Rab27a

Hintergrund:

Goat polyclonal antibody to mouse Rab27a. Rab27a belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and involved in lysosome-related vesicle transport and small GTPase mediated signal transduction.

GS2, GTP-binding protein Ram, rab-27, ras-related protein Rab-27A, RAB27, RAM antibody.

Pathways: Peptide Hormone Metabolism