IGSF3 Antikörper (PE-Cy5.5)

Produktnummer ABIN1434910

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IGSF3 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund und Schwein.

Kurzübersicht für IGSF3 Antikörper (PE-Cy5.5) (ABIN1434910)

Target: IGSF3 (Immunoglobulin Superfamily, Member 3 (IGSF3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IGSF3 Antikörper ist konjugiert mit PE-Cy5.5

Applikation: Western Blotting (WB)

Produktdetails anti-IGSF3 Antikörper (PE-Cy5.5)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IGSF3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu IGSF3

Target: IGSF3 (Immunoglobulin Superfamily, Member 3 (IGSF3))

Andere Bezeichnung: IGSF3

Hintergrund:

Synonyms: EWI 3, EWI3, Glu Trp Ile EWI mot containing protein 3, Immunoglobin superfamily member 3, Immunoglobulin superfamily member 3, KIAA0466, MGC117164, V8 antibody, IGSF3_HUMAN.

Background: IGSF3, also known as V8 or EWI-3, is a 1,214 amino acid protein. Widely expressed with predominant expression in kidney, placenta and lung, IGSF3 localizes to the membrane and contains an N-terminal signal peptide, eight immunoglobulin (Ig) domains and a transmembrane segment. IGSF3 exhibits strong sequence and structural similarity to CD101 (32 % identity), a leukocyte surface protein with seven Ig domains that is believed to play a role in T-cell activation. Despite the structural similarities between IGSF3 and CD101, IGSF3 is not expressed in peripheral blood lymphocytes and does not appear to participate in an immune function. Based on its subcellular localization and the presence of the eight Ig domains, IGSF3 is hypothesized to function as a surface receptor or as a cell adhesion molecule.

Molekulargewicht: 135kDa

Gen-ID: 3321

UniProt: O75054