ZNRF3 Antikörper (PE-Cy5)

Produktnummer ABIN1434639

Dieses Anti-ZNRF3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ZNRF3 in IF (p). Geeignet für Human, Maus, Ratte, Huhn, Rind (Kuh), Hund und Schwein.

Kurzübersicht für ZNRF3 Antikörper (PE-Cy5) (ABIN1434639)

Target: ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))

Reaktivität: Human, Maus, Ratte, Huhn, Rind (Kuh), Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZNRF3 Antikörper ist konjugiert mit PE-Cy5

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-ZNRF3 Antikörper (PE-Cy5)

Kreuzreaktivität: Ratte (Rattus), Huhn, Hund, Schwein, Rind (Kuh)

Aufreinigung: purified by Protein A

Immunogen: KLH conjugated synthetic peptide derived from human ZNRF3

Isotyp: IgG

Anwendungsinformationen

Kommentare:

Excitation / Emission wavelength: 496nm / 556nm

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4 °C for 12 months

Haltbarkeit: 12 months

Details zu ZNRF3

Target: ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))

Andere Bezeichnung: ZNRF3

Hintergrund: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). ZNRF3 (Zinc/RING finger protein 3), also known as RNF203 (RING finger protein 203), is a 936 amino acid single pass transmembrane protein that contains one RING-type zinc finger. Related zinc/RING finger proteins, such as ZNRF1 and ZNRF2, are E3 ubiquitin-protein ligases that are thought to be involved in the establishment and maintenance of neuronal transmission and plasticity, therefore it is likely that ZNRF3 may function in a similar manner.

Gen-ID: 84133

HGNC: 0

Pathways: WNT Signalweg