Vangl1 Antikörper (PE-Cy7)

Produktnummer ABIN1433386

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Vangl1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Schwein und Huhn.

Kurzübersicht für Vangl1 Antikörper (PE-Cy7) (ABIN1433386)

Target: Vangl1 (Vang-Like 1 (Vangl1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Vangl1 Antikörper ist konjugiert mit PE-Cy7

Applikation: Western Blotting (WB)

Produktdetails anti-Vangl1 Antikörper (PE-Cy7)

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human VANGL1/LPP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Vangl1

Target: Vangl1 (Vang-Like 1 (Vangl1))

Andere Bezeichnung: VANGL1/LPP2

Hintergrund:

Synonyms: Loop tail protein 2 homolog, Loop-tail protein 2 homolog, LPP2, MGC5338, STB2, STBM2, Strabismus 2, Van Gogh like protein 1, Van Gogh-like protein 1, vang like 1 van gogh, Drosophila, Vang like protein 1, Vang-like protein 1, VANG1_HUMAN, VANGL 1, Vangl1.

Background: The Vang family of proteins are integral membrane proteins that are homologues of the Drosophila tissue polarity gene strabismus. The gene encoding for Van Gogh-like protein 1 (Vangl1), also designated Strabismus 2 (STB2), localizes to human chromosome 1p11-p13.1. Van Gogh-like protein 2 (Vangl2), also designated Strabismus 1 (STB1), localizes to chromosome 1q22-q23. Vangl1 is expressed primarily in testis and ovary, but is also expressed in gastric and pancreatic cancer. Vangl proteins play a key developmental role in establishing planar cell polarity (PCP) and in regulating convergent extension (CE) movements during embryogenesis. Vangl1 and Vangl2 are both downregulated in several cancer cell lines and primary tumors.

Molekulargewicht: 60 kDa

Gen-ID: 8612

Pathways: WNT Signalweg