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FAS Antikörper (AA 81-170) (PE)

FAS Reaktivität: Human, Ratte, Maus WB, FACS Wirt: Kaninchen Polyclonal PE
Produktnummer ABIN1431676
  • Target Alle FAS Antikörper anzeigen
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    Bindungsspezifität
    • 24
    • 16
    • 15
    • 9
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 81-170
    Reaktivität
    • 220
    • 62
    • 62
    • 19
    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 155
    • 99
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 155
    • 109
    • 1
    Polyklonal
    Konjugat
    • 118
    • 28
    • 25
    • 12
    • 12
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FAS Antikörper ist konjugiert mit PE
    Applikation
    • 156
    • 125
    • 71
    • 59
    • 38
    • 35
    • 29
    • 26
    • 26
    • 19
    • 16
    • 11
    • 8
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human FAS/Apo-1
    Isotyp
    IgG
    Top Product
    Discover our top product FAS Primärantikörper
  • Applikationshinweise
    FCM 1:20-100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    Andere Bezeichnung
    Apo-1 (FAS Produkte)
    Synonyme
    ALPS1A antikoerper, APO-1 antikoerper, APT1 antikoerper, CD95 antikoerper, FAS1 antikoerper, FASTM antikoerper, TNFRSF6 antikoerper, AI196731 antikoerper, APO1 antikoerper, TNFR6 antikoerper, Tnfrsf6 antikoerper, lpr antikoerper, Fas cell surface death receptor antikoerper, Fas (TNF receptor superfamily member 6) antikoerper, FAS antikoerper, Fas antikoerper, fas antikoerper
    Hintergrund

    Synonyms: APT1, CD95, FAS1, APO-1, FASTM, ALPS1A, TNFRSF6, Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor, FAS

    Background: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

    Molekulargewicht
    34kDa
    Gen-ID
    355
    UniProt
    P25445
    Pathways
    p53 Signalweg, Apoptose, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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