M-CSF/CSF1 Antikörper (PE-Cy5)

Produktnummer ABIN1431263

Der Kaninchen Polyklonal Anti-M-CSF/CSF1-Antikörper wurde für WB validiert. Er ist geeignet, M-CSF/CSF1 in Proben von Human, Maus, Ratte, Hund, Schwein und Rind (Kuh) zu detektieren.

Kurzübersicht für M-CSF/CSF1 Antikörper (PE-Cy5) (ABIN1431263)

Target: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser M-CSF/CSF1 Antikörper ist konjugiert mit PE-Cy5

Applikation: Western Blotting (WB)

Produktdetails anti-M-CSF/CSF1 Antikörper (PE-Cy5)

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MCSF

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu M-CSF/CSF1

Target: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Andere Bezeichnung: MCSF

Hintergrund:

Synonyms: MCSF, CSF-1, Macrophage colony-stimulating factor 1, M-CSF, Lanimostim, CSF1

Background: Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.

Molekulargewicht: 57kDa

Gen-ID: 1435

UniProt: P09603

Pathways: RTK Signalweg