HTR1F Antikörper (PE-Cy7)

Produktnummer ABIN1429474

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HTR1F in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Rind (Kuh), Schwein und Hund.

Kurzübersicht für HTR1F Antikörper (PE-Cy7) (ABIN1429474)

Target: HTR1F (5-Hydroxytryptamine (serotonin) Receptor 1F (HTR1F))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Schwein, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HTR1F Antikörper ist konjugiert mit PE-Cy7

Applikation: Western Blotting (WB)

Produktdetails anti-HTR1F Antikörper (PE-Cy7)

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Sheep,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human 5HT1F Receptor/SR-1F

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu HTR1F

Target: HTR1F (5-Hydroxytryptamine (serotonin) Receptor 1F (HTR1F))

Hintergrund:

Synonyms: 5 HT 1F, 5 HT1F, 5 hydroxytryptamine serotonin receptor 1F, 5 hydroxytryptamine 1F receptor, 5 hydroxytryptamine receptor 1E beta, 5 hydroxytryptamine receptor 1F, 5 hydroxytryptamine serotonin receptor 1E beta, 5 hydroxytryptamine serotonin receptor 1F, 5HT 1F, 5HT1F, HTR 1F, HTR1EB, HTR1EL, HTR1F, MR 77, MR77, Serotonin receptor 1E beta, Serotonin receptor gene, 5HT1F_HUMAN.

Background: The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. b-adrenergic bound to adrenaline activates adenylyl cyclase, while a2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the a2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-17 (5HT17). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.

Molekulargewicht: 42kDa

Pathways: JAK-STAT Signalweg