5HT1D Antikörper (PE)

Produktnummer ABIN1429460

Der Kaninchen Polyklonal Anti-5HT1D-Antikörper wurde für FACS validiert. Er ist geeignet, 5HT1D in Proben von Maus, Human und Ratte zu detektieren.

Kurzübersicht für 5HT1D Antikörper (PE) (ABIN1429460)

Target: 5HT1D (HTR1D) (Serotonin Receptor 1D (HTR1D))

Reaktivität: Maus, Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser 5HT1D Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-5HT1D Antikörper (PE)

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human 5HT1D Receptor/SR-1D

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM: 1:20-100
Optimal working dilution should be determined by the investigator.

Kommentare:

Exitation/Emission: 480,565nm/578nm

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4 °C

Haltbarkeit: 12 months

Details zu 5HT1D

Target: 5HT1D (HTR1D) (Serotonin Receptor 1D (HTR1D))

Hintergrund:

The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. b-adrenergic bound to adrenaline activates adenylyl cyclase, while a2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the a2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-1â€"7 (5HT1â€"7). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.

Subcellular location: Extracellular

Synonyms: 5 HT 1D alpha, 5 HT 1D, 5 HT1B, 5 HT1D, 5HT1D, 5 hydroxytryptamine serotonin receptor 1B, 5 hydroxytryptamine serotonin receptor 1D G protein coupled, 5 hydroxytryptamine 1B receptor 5 HT 1B Serotonin receptor 5 HT 1D beta Serotonin 1D beta receptor S12, 5 hydroxytryptamine receptor 1D, HT1DA, HTR1D, HTR1D2, HTR1DA, HTRL, RDC4, S12, Serotonin receptor 1D, 5HT1D_HUMAN.

Pathways: JAK-STAT Signalweg