Metabotropic Glutamate Receptor 1 Antikörper (PE)

Produktnummer ABIN1429290

Dieses Anti-Metabotropic Glutamate Receptor 1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Metabotropic Glutamate Receptor 1 in . Geeignet für Human, Maus und Ratte.

Kurzübersicht für Metabotropic Glutamate Receptor 1 Antikörper (PE) (ABIN1429290)

Target: Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Metabotropic Glutamate Receptor 1 Antikörper ist konjugiert mit PE

Applikation: Bitte anfragen

Produktdetails anti-Metabotropic Glutamate Receptor 1 Antikörper (PE)

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MGLUR1A/Metabotropic Glutamate Receptor 1a

Isotyp: IgG

Anwendungsinformationen

Kommentare:

Exitation/Emission: 480,565nm/578nm

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4°C

Haltbarkeit: 12 months

Details zu Metabotropic Glutamate Receptor 1

Target: Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))

Andere Bezeichnung: MGLUR1A

Hintergrund:

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternative splice variants of the GRM1 gene have been described but their full-length nature has not been determined.

Subcellular location: Extracellular

Synonyms: G protein coupled receptor family C group 1 member A, Glutamate receptor metabotropic 1 alpha, Glutamate receptor metabotropic 1, GPRC1A, GRM 1, GRM1 alpha, GRM1, GRM1A, Human metabotropic glutamate receptor 1 alpha mRNA complete cds, Metabotropic glutamate receptor 1 alpha, Metabotropic glutamate receptor 1, mGlu1, MGLUR1, MGLUR1A, mGluR1alpha.