EPH Receptor B3 Antikörper (PE-Cy5)

Produktnummer ABIN1425707

Der Kaninchen Polyklonal Anti-EPH Receptor B3-Antikörper wurde für WB validiert. Er ist geeignet, EPH Receptor B3 in Proben von Human, Maus, Ratte, Huhn, Schwein, Rind (Kuh) und Hund zu detektieren.

Kurzübersicht für EPH Receptor B3 Antikörper (PE-Cy5) (ABIN1425707)

Target: EPH Receptor B3 (EPHB3)

Reaktivität: Human, Maus, Ratte, Huhn, Schwein, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor B3 Antikörper ist konjugiert mit PE-Cy5

Applikation: Western Blotting (WB)

Produktdetails anti-EPH Receptor B3 Antikörper (PE-Cy5)

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EPHB3/Eph receptor B3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu EPH Receptor B3

Target: EPH Receptor B3 (EPHB3)

Andere Bezeichnung: EPHB3/Eph receptor B3

Hintergrund:

Synonyms: Cek10, EK2, Embryonic kinase 2, EPH Like Tyrosine Kinase 2, EPH-like kinase 2, ephb3, EPHB3_HUMAN, Ephrin receptor EphB3, Ephrin type B receptor 3, Ephrin type-B receptor 3, ETK2, hEK2, Human Embryo Kinase 2, Mdk5, Sek4, TYRO6, Tyrosine protein kinase receptor HEK2, Tyrosine protein kinase TYRO6, Tyrosine-protein kinase TYRO6.

Background: The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date (13). While the biological activities of these receptors have yet to be determined, there is increasing evidence that they are involved in central nervous system function and in development (13). The Eph subfamily receptors of human origin (and their murine/avian homologs) include EphA1 (Eph), EphA2 (Eck), EphA3 (Hek4), EphA4 (Hek8), EphA5 (Hek7), EphA6 (Hek12), EphA7 (Hek11/MDK1), EphA8 (Hek3), EphB1 (Hek6), EphB2 (Hek5), EphB3 (Cek10, Hek2), EphB4 (Htk), EphB5 (Hek9) and EphB6 (Mep). Ligands for Eph receptors include ephrin-A4 (LERK-4) which binds EphA3 and EphB1. In addition, ephrin-A2 (ELF-1) has been described as the ligand for EphA4, ephrin-A3 (Ehk1-L) as the ligand for EphA5 and ephrin-B2 (Htk-L) as the ligand for EphB4 (Htk) (47).

Molekulargewicht: 110kDa

Pathways: RTK Signalweg