AIDA Antikörper (Cy5.5)

Produktnummer ABIN1422619

This anti-AIDA antibody (ABIN1422619) is a Rabbit Polyclonal antibody detecting AIDA in WB, IF (p). Suitable for Human, Mouse, Rat.

Quick Overview for AIDA Antikörper (Cy5.5) (ABIN1422619)

Target: AIDA (Axin Interactor, Dorsalization Associated (AIDA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AIDA Antikörper ist konjugiert mit Cy5.5

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-AIDA Antikörper (Cy5.5)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf180/AIDA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu AIDA

Target: AIDA (Axin Interactor, Dorsalization Associated (AIDA))

Andere Bezeichnung: C1orf80

Hintergrund:

Synonyms: dorsalization-associated protein, AIDA, AIDA_HUMAN, Axin interaction partner and dorsalization antagonist, Axin interactor, Axin interactor, dorsalization associated, Chromosome 1 open reading frame 80, UPF0491 protein C1orf80.

Background: AIDA, also known as C1orf80, is a 306 amino acid protein that belongs to the axin interactor family. Expressed in a variety of tissues, including skeletal muscle and heart, AIDA functions as a ventralizing factor during embryogenesis, disrupting Axin homodimerization and inhibiting Axin-mediated JNK activation. Axin, a scaffold protein, is important for both JNK signaling and the canonical Wnt pathway, two processes that play an essential role in embryonic dorsoventral patterning. Disruption of Axin by AIDA results in the negative regulation of JNK and Wnt signaling, thereby affecting embryonic developmental events. Three isoforms of AIDA exist due to alternative splicing events.

Gen-ID: 439927