ZNRF3 Antikörper (AA 120-165) (Cy3)
Kurzübersicht für ZNRF3 Antikörper (AA 120-165) (Cy3) (ABIN1418939)
Target
Alle ZNRF3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 120-165
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human ZNRF3
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Isotyp
- IgG
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anti-Zinc and Ring Finger Protein 3 (ZNRF3) (AA 56-219) antibody
ZNRF3 Reaktivität: Human ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Zinc and Ring Finger Protein 3 (ZNRF3) (AA 120-165) antibodyZNRF3 Reaktivität: Human, Maus, Ratte IF (p), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- IF(IHC-P) 1:50-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))
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Andere Bezeichnung
- ZNRF3
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Hintergrund
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Synonyms: RNF203, BK747E2.3, E3 ubiquitin-protein ligase ZNRF3, RING finger protein 203, Zinc/RING finger protein 3, ZNRF3, KIAA1133
Background: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
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Gen-ID
- 84133
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UniProt
- Q9ULT6
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Pathways
- WNT Signalweg
Target
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