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COPS4 Antikörper (Cy3)

COPS4 Reaktivität: Human, Maus, Ratte WB, IF (p) Wirt: Kaninchen Polyclonal Cy3
Produktnummer ABIN1418831
  • Target Alle COPS4 Antikörper anzeigen
    COPS4 (COP9 Signalosome Subunit 4 (COPS4))
    Reaktivität
    • 24
    • 22
    • 21
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 24
    Kaninchen
    Klonalität
    • 24
    Polyklonal
    Konjugat
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser COPS4 Antikörper ist konjugiert mit Cy3
    Applikation
    • 24
    • 12
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human COPS4
    Isotyp
    IgG
    Top Product
    Discover our top product COPS4 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    COPS4 (COP9 Signalosome Subunit 4 (COPS4))
    Andere Bezeichnung
    COPS4 (COPS4 Produkte)
    Synonyme
    CG8725 antikoerper, CH4 antikoerper, Cops4 antikoerper, Csn4 antikoerper, DCH4 antikoerper, Dch4 antikoerper, Dmel\\CG8725 antikoerper, csn4 antikoerper, l(2)k08018 antikoerper, COPS4 antikoerper, SGN4 antikoerper, DKFZp459H0324 antikoerper, AW208976 antikoerper, D5Ertd774e antikoerper, fc90c08 antikoerper, wu:fc90c08 antikoerper, zgc:77137 antikoerper, ATS4 antikoerper, CONSTITUTIVE PHOTOMORPHOGENIC 14 antikoerper, CONSTITUTIVE PHOTOMORPHOGENIC 8 antikoerper, COP14 antikoerper, COP9 SIGNALOSOME SUBUNIT 4 antikoerper, CSN4 antikoerper, EMB134 antikoerper, EMBRYO DEFECTIVE 134 antikoerper, FUS4 antikoerper, FUS8 antikoerper, FUSCA 4 antikoerper, FUSCA 8 antikoerper, MBD2.17 antikoerper, MBD2_17 antikoerper, COS41.8 antikoerper, COP9 signalosome subunit 4 antikoerper, COP9 signalosome complex subunit 4 antikoerper, COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) antikoerper, Proteasome component (PCI) domain protein antikoerper, COP9 signalosome subunit 4 L homeolog antikoerper, CSN4 antikoerper, COPS4 antikoerper, CpipJ_CPIJ000966 antikoerper, csn4 antikoerper, Cops4 antikoerper, cops4 antikoerper, COP8 antikoerper, cops4.L antikoerper, csn-4 antikoerper
    Hintergrund

    Synonyms: CH4, COP9 constitutive photomorphogenic homolog subunit 4, COP9 complex homolog subunit 4, COP9 complex S4, COP9 constitutive photomorphogenic homolog subunit 4, COP9 signalosome complex subunit 4, COP9 signalosome subunit 4, COPS4, CSN complex subunit 4, CSN4, CSN4 SCHPO, CSN4_HUMAN, DCH4, JAB1 containing signalosome subunit 4, JAB1-containing signalosome subunit 4, MGC94896, SGN4, Signalosome subunit 4.

    Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

    Gen-ID
    51138
    Pathways
    Zellzyklus
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