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ELL3 Antikörper (AA 51-158) (Cy7)

This anti-ELL3 antibody (ABIN1417598) is a Rabbit Polyclonal antibody detecting ELL3 in IF (cc), IF (p). Suitable for Human.
Produktnummer ABIN1417598

Quick Overview for ELL3 Antikörper (AA 51-158) (Cy7) (ABIN1417598)

Target

Alle ELL3 Antikörper anzeigen
ELL3 (Elongation Factor RNA Polymerase II-Like 3 (ELL3))

Reaktivität

  • 28
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 26
  • 2
Kaninchen

Klonalität

  • 28
Polyklonal

Konjugat

  • 10
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ELL3 Antikörper ist konjugiert mit Cy7

Applikation

  • 14
  • 12
  • 12
  • 11
  • 3
  • 3
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-158

    Homologie

    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human ELL3

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    ELL3 (Elongation Factor RNA Polymerase II-Like 3 (ELL3))

    Andere Bezeichnung

    ELL3

    Hintergrund

    Synonyms: B cell translocation gene 2, BTG family member 2, Btg2, BTG2_HUMAN, Nerve growth factor inducible anti prolerative, NGF inducible anti prolerative protein PC3, NGF-inducible anti-prolerative protein PC3, PC3, Pheochromacytoma cell 3, Protein BTG2, TIS21.

    Background: Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle, that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein), also designated MEN, functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. It is also thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, with lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary. ELL3 is a 397 amino acid nuclear protein that functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. Though similar to ELL and ELL2, ELL3 is exclusively expressed in testis.

    Gen-ID

    80237

    Pathways

    Negative Regulation of intrinsic apoptotic Signaling
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