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ELL3 Antikörper (AA 51-158) (Biotin)

ELL3 Reaktivität: Human ELISA, IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1399729
  • Target Alle ELL3 Antikörper anzeigen
    ELL3 (Elongation Factor RNA Polymerase II-Like 3 (ELL3))
    Bindungsspezifität
    • 14
    • 8
    • 8
    • 6
    • 1
    • 1
    • 1
    • 1
    AA 51-158
    Reaktivität
    • 33
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 31
    • 2
    Kaninchen
    Klonalität
    • 33
    Polyklonal
    Konjugat
    • 10
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ELL3 Antikörper ist konjugiert mit Biotin
    Applikation
    • 19
    • 15
    • 13
    • 13
    • 2
    • 2
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ELL3
    Isotyp
    IgG
    Top Product
    Discover our top product ELL3 Primärantikörper
  • Applikationshinweise
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    ELL3 (Elongation Factor RNA Polymerase II-Like 3 (ELL3))
    Andere Bezeichnung
    ELL3 (ELL3 Produkte)
    Synonyme
    DKFZp469F0639 antikoerper, A930015D22Rik antikoerper, elongation factor for RNA polymerase II 3 antikoerper, elongation factor RNA polymerase II-like 3 L homeolog antikoerper, elongation factor RNA polymerase II-like 3 antikoerper, ELL3 antikoerper, ell3.L antikoerper, Ell3 antikoerper
    Hintergrund

    Synonyms: B cell translocation gene 2, BTG family member 2, Btg2, BTG2_HUMAN, Nerve growth factor inducible anti prolerative, NGF inducible anti prolerative protein PC3, NGF-inducible anti-prolerative protein PC3, PC3, Pheochromacytoma cell 3, Protein BTG2, TIS21.

    Background: Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle, that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein), also designated MEN, functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. It is also thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, with lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary. ELL3 is a 397 amino acid nuclear protein that functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. Though similar to ELL and ELL2, ELL3 is exclusively expressed in testis.

    Gen-ID
    80237
    Pathways
    Negative Regulation of intrinsic apoptotic Signaling
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