APLP2 Antikörper (AA 501-600) (HRP)

Produktnummer ABIN1417102

Produktdetails anti-APLP2 Antikörper (HRP)

Target: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Bindungsspezifität: AA 501-600

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APLP2 Antikörper ist konjugiert mit HRP

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human APLP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu APLP2

Target: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Andere Bezeichnung: APLP2 (APLP2 Produkte)

Synonyme: HAI antikoerper, MT-SP1 antikoerper, MTSP1 antikoerper, PRSS14 antikoerper, SNC19 antikoerper, TADG15 antikoerper, TMPRSS14 antikoerper, APLP-2 antikoerper, APPH antikoerper, APPL2 antikoerper, CDEBP antikoerper, AI790698 antikoerper, Apph antikoerper, WALPLP2 antikoerper, aplp2 B antikoerper, APLP2 antikoerper, si:dkey-11k4.3 antikoerper, aplp2 A antikoerper, MGC86389 antikoerper, suppression of tumorigenicity 14 antikoerper, amyloid beta precursor like protein 2 antikoerper, amyloid beta (A4) precursor-like protein 2 antikoerper, amyloid beta (A4) precursor-like protein 2 S homeolog antikoerper, amyloid beta (A4) precursor-like protein 2 L homeolog antikoerper, ST14 antikoerper, APLP2 antikoerper, Aplp2 antikoerper, aplp2.S antikoerper, aplp2 antikoerper, aplp2.L antikoerper

Hintergrund:

Synonyms: amyloid beta A4 precursor like protein 2, Amyloid like protein 2, amyloid precursor protein homolog HSD2, Amyloid protein homolog, Amyloid-like protein 2, APLP-2, Aplp2, APLP2_HUMAN, APPH, APPL2, CDEBP, CDEI box binding protein, CDEI box-binding protein.

Background: APLP2 is a human sperm membrane protein which contains a segment with high homology to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer disease patients. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. The gene which encodes APLP2 maps to human chromosome 11q24.May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.

Gen-ID: 334

Pathways: EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Feeding Behaviour