DENND1B Antikörper (AA 241-350) (Cy5)
Kurzübersicht für DENND1B Antikörper (AA 241-350) (Cy5) (ABIN1415958)
Target
Alle DENND1B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 241-350
-
Kreuzreaktivität
- Maus
-
Homologie
- Human,Rat,Dog,Cow,Horse,Rabbit
-
Aufreinigung
- Purified by Protein A.
-
Immunogen
- KLH conjugated synthetic peptide derived from human DENND1B
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 μg/μL
-
Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
Haltbarkeit
- 12 months
-
-
- DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
-
Andere Bezeichnung
- DENND1B
-
Hintergrund
-
Synonyms: C1ORF18, C1orf218, Chromosome 1 open reading frame 218, Connecdenn 2, DEN1B_HUMAN, DENN domain containing protein 1B, DENN domain-containing protein 1B, DENN MADD domain containing 1B, DENND1B, DKFZp547O0715, FAM31B, Family with sequence similarity 31 member B, FLJ20054, FLJ21179, FLJ33888, MGC103810, MGC27044, Protein FAM31B
Background: Guanine nucleotide exchange factor (GEF) for RAB35. May function as a clathrin-associated sorting protein for RAB35, whereby during clathrin-mediated endocytosis, binds the AP-2 complex and inactived RAB35, then activates RAB35 for its subsequent function at endosomes.Tissue specificity:Highly expressed in dendritic and natural killer cells and at lower levels in other myeloid lineage cells and in pituitary. Significantly up-regulated in effector memory T cells as compared with naive T cells.
-
Gen-ID
- 163486
-
UniProt
- Q6P3S1
Target
-