RPGRIP1L Antikörper (AA 41-140) (HRP)

Produktnummer ABIN1412144

Der Kaninchen Polyklonal Anti-RPGRIP1L-Antikörper wurde für WB, ELISA, IHC (fro) und IHC (p) validiert. Er ist geeignet, RPGRIP1L in Proben von Human zu detektieren.

Kurzübersicht für RPGRIP1L Antikörper (AA 41-140) (HRP) (ABIN1412144)

Target: RPGRIP1L (RPGRIP1-Like (RPGRIP1L))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPGRIP1L Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-RPGRIP1L Antikörper (HRP)

Bindungsspezifität: AA 41-140

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RPGRIP1L

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu RPGRIP1L

Target: RPGRIP1L (RPGRIP1-Like (RPGRIP1L))

Andere Bezeichnung: RPGRIP1L

Hintergrund:

Synonyms: CORS 3, CORS3, Fantom, FTM, JBTS 1, JBTS 7, JBTS1, JBTS7, Joubert syndrome 1, Joubert syndrome 7, Meckel syndrome, type 1, RPGRIP1-like, Meckel syndrome, type 5, MKS 5, MKS5, NPHP 8, NPHP8, nephrocystin 8, Protein fantom, Retinitis pigmentosa GTPase regulator interacting protein 1 like, RPGR interacting protein 1 like protein, RPGRIP1 like protein, FTM_HUMAN.

Background: RPGRIP1L is a 1,315 amino acid protein that belongs to the RPGRIP1 family and is thought to function in programmed cell death, craniofacial development and formation of the left-right axis. Existing as two alternatively spliced isoforms that localize to the cytoplasm, cytoskeleton, centrosome and cilium basal body, RPGRIP1L interacts with nephrocystin-4 and is moderately expressed in brain, retina and kidney. Containing two C2 domains, RPGRIP1L is encoded by a gene that maps to human chromosome 16q12.2. Defects in the gene encoding RPGRIP1L are the cause of Joubert syndrome type 7 (JBTS7), COACH syndrome (COACHS) and Meckel syndrome type 5 (MKS5).

Pathways: DNA Replication, Regulation of G-Protein Coupled Receptor Protein Signaling, Synthesis of DNA