RPGRIP1L Antikörper (N-Term)

Produktnummer ABIN6264825

Produktdetails anti-RPGRIP1L Antikörper

Target: RPGRIP1L (RPGRIP1-Like (RPGRIP1L))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPGRIP1L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: RPGRIP1L Antibody detects endogenous levels of total RPGRIP1L.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RPGRIP1L, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu RPGRIP1L

Target: RPGRIP1L (RPGRIP1-Like (RPGRIP1L))

Andere Bezeichnung: RPGRIP1L (RPGRIP1L Produkte)

Synonyme: si:ch1073-301i20.1 antikoerper, mks5 antikoerper, cors3 antikoerper, jbts7 antikoerper, nphp8 antikoerper, CORS3 antikoerper, FTM antikoerper, JBTS7 antikoerper, MKS5 antikoerper, NPHP8 antikoerper, 1700047E16Rik antikoerper, 4931437C01 antikoerper, Ftm antikoerper, Nphp8 antikoerper, RGD1311099 antikoerper, RPGRIP1 like antikoerper, RPGRIP1-like antikoerper, Protein fantom antikoerper, Rpgrip1-like antikoerper, RPGRIP1L antikoerper, rpgrip1l antikoerper, mks-5 antikoerper, Rpgrip1l antikoerper

Hintergrund:

Description: Negatively regulates signaling through the G-protein coupled thromboxane A2 receptor (TBXA2R) (PubMed:19464661). May be involved in mechanisms like programmed cell death, craniofacial development, patterning of the limbs, and formation of the left-right axis (By similarity). Involved in the organization of apical junctions, the function is proposed to implicate a NPHP1-4-8 module. Does not seem to be strictly required for ciliogenesis (PubMed:19464661). Involved in establishment of planar cell polarity such as in cochlear sensory epithelium and is proposed to implicate stabilization of disheveled proteins (By similarity). Involved in regulation of proteasomal activity at the primary cilium probably implicating association with PSDM2 (By similarity).

Gene: RPGRIP1L

Molekulargewicht: 151 kDa

Gen-ID: 23322

UniProt: Q68CZ1

Pathways: DNA Replication, Regulation of G-Protein Coupled Receptor Protein Signaling, Synthesis of DNA