LMCD1 Antikörper (AA 51-160) (HRP)

Produktnummer ABIN1411730

Produktdetails anti-LMCD1 Antikörper (HRP)

Target: LMCD1 (LIM and Cysteine-Rich Domains 1 (LMCD1))

Bindungsspezifität: AA 51-160

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LMCD1 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LMCD1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu LMCD1

Target: LMCD1 (LIM and Cysteine-Rich Domains 1 (LMCD1))

Andere Bezeichnung: LMCD1 (LMCD1 Produkte)

Synonyme: LMCD1 antikoerper, AW455500 antikoerper, AW553074 antikoerper, dyxin antikoerper, LIM and cysteine rich domains 1 antikoerper, LIM and cysteine-rich domains 1 antikoerper, LMCD1 antikoerper, lmcd1 antikoerper, Lmcd1 antikoerper

Hintergrund:

Synonyms: Dyxin, LIM and cysteine rich domains 1, LIM and cysteine rich domains protein 1, LIM and cysteine-rich domains protein 1, LMCD1_HUMAN.

Background: Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T cells signaling pathway.