LMCD1 Antikörper (C-Term)

Produktnummer ABIN6243246

Produktdetails anti-LMCD1 Antikörper

Target: LMCD1 (LIM and Cysteine-Rich Domains 1 (LMCD1))

Bindungsspezifität: AA 316-350, C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LMCD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LMCD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 316-350 amino acids from the C-terminal region of human LMCD1.

Klon: RB40473

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu LMCD1

Target: LMCD1 (LIM and Cysteine-Rich Domains 1 (LMCD1))

Andere Bezeichnung: LMCD1 (LMCD1 Produkte)

Synonyme: LMCD1 antikoerper, AW455500 antikoerper, AW553074 antikoerper, dyxin antikoerper, LIM and cysteine rich domains 1 antikoerper, LIM and cysteine-rich domains 1 antikoerper, LMCD1 antikoerper, lmcd1 antikoerper, Lmcd1 antikoerper

Hintergrund: Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue- specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.

Molekulargewicht: 40833

UniProt: Q9NZU5