RCAN1 Antikörper (AA 101-200) (Cy7)

Produktnummer ABIN1409772

Dieses Anti-RCAN1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RCAN1 in WB, IF (cc) und IF (p). Geeignet für Human.

Kurzübersicht für RCAN1 Antikörper (AA 101-200) (Cy7) (ABIN1409772)

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RCAN1 Antikörper ist konjugiert mit Cy7

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-RCAN1 Antikörper (Cy7)

Bindungsspezifität: AA 101-200

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Calcipressin 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu RCAN1

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Andere Bezeichnung: Calcipressin 1/DSCR 1

Hintergrund:

Synonyms: Adapt 78, Adapt78, Calcipressin 1, Calcipressin-1, Calcium and oxidant inducible mRNA, CSP 1, CSP1, Down syndrome candidate region 1, Down syndrome critical region gene 1, Down syndrome critical region protein 1, DSC 1, DSC1, DSCR 1, DSCR1, DSCR-1, MCIP 1, MCIP1, Modulatory calcineurin interacting protein 1, Myocyte enriched calcineurin interacting protein 1, Myocyte-enriched calcineurin-interacting protein 1, Near DSCR proline rich protein, RCAN1, RCAN1_HUMAN, RCN 1, RCN1, Regulator of calcineurin 1.

Background: DSCR1 protein influences cardiac and nervous system development (1). DSCR1 is abundant in the brain, heart, and skeletal muscle. Overexpression of DSCR1 may play a role in the pathogenesis of Down syndrome, in particular mental retardation and/or cardiac defects. DSCR1 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Human DSCR1 maps to gene locus 21q22.1-q22.2.

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development