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BBS9 Antikörper (AA 244-320) (Cy5)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BBS9 in IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Ratte.
Produktnummer ABIN1409590

Kurzübersicht für BBS9 Antikörper (AA 244-320) (Cy5) (ABIN1409590)

Target

Alle BBS9 Antikörper anzeigen
BBS9 (Bardet-Biedl Syndrome 9 (BBS9))

Reaktivität

  • 27
  • 16
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Ratte

Wirt

  • 41
Kaninchen

Klonalität

  • 41
Polyklonal

Konjugat

  • 13
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser BBS9 Antikörper ist konjugiert mit Cy5

Applikation

  • 17
  • 15
  • 12
  • 12
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 8
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 244-320

    Kreuzreaktivität

    Ratte

    Homologie

    Human,Mouse,Dog,Sheep,Pig,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human BBS9

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    BBS9 (Bardet-Biedl Syndrome 9 (BBS9))

    Andere Bezeichnung

    BBS9

    Hintergrund

    Synonyms: B1, D1, C18, PTHB1, Protein PTHB1, Bardet-Biedl syndrome 9 protein, Parathyroid hormone-responsive B1 gene protein, BBS9

    Background: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization.

    Gen-ID

    27241

    UniProt

    Q3SYG4

    Pathways

    Hedgehog Signalweg
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