NMUR1 Antikörper (AA 31-80) (Cy3)

Produktnummer ABIN1409061

Dieses Anti-NMUR1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NMUR1 in FACS. Geeignet für Human, Maus und Ratte.

Kurzübersicht für NMUR1 Antikörper (AA 31-80) (Cy3) (ABIN1409061)

Target: NMUR1 (Neuromedin U Receptor 1 (NMUR1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NMUR1 Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-NMUR1 Antikörper (Cy3)

Bindungsspezifität: AA 31-80

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NMUR1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NMUR1

Target: NMUR1 (Neuromedin U Receptor 1 (NMUR1))

Andere Bezeichnung: NMUR1/GPR66

Hintergrund:

Synonyms: FM-3, G protein-coupled receptor 66, G-protein coupled receptor 66, G-protein coupled receptor FM-3, GPR66, Growth hormone secretagogue receptor family Member 3, Neuromedin U Receptor 1, Neuromedin-U receptor 1, NMU-R1, NMUR1, NMUR1_HUMAN.

Background: Neuromedin U is a neuropeptide with high activity on smooth muscle. It is widely expressed in gastrointestinal systems and central nervous system (CNS). Peripheral activities of neuromedin U include smooth muscle stimulation, ion transport alterations in the gut and the regulation of local blood flow and adrenocortical function. Neuromedin U receptors 1 and 2 (NMUR1 and NMUR2) are multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family of proteins. Both NMUR1 and NMUR2 act as receptors for the neuromedin U neuropeptide. NMUR1 is detected in peripheral organs, particularly in urogenital and gastrointestinal systems, with highest levels in testis. It?s expression in CNS is low, but the protein has been detected in cerebellum, hippocampus, dorsal root ganglia and spinal cord. NMUR2 is predominantly detected in central nervous system with highest levels detected in medulla oblongata, spinal cord and thalamus. It may also be detected in testis but has low levels of expression in peripheral tissues.

Gen-ID: 10316

UniProt: Q9HB89