NMUR1 Antikörper (Extracellular, Loop 3)

Produktnummer ABIN7886649

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch NMUR1 in WB, FACS, IHC und LCI. Es zeigt Reaktivität gegenüber Proben von Ratte.

Kurzübersicht für NMUR1 Antikörper (Extracellular, Loop 3) (ABIN7886649)

Target: NMUR1 (Neuromedin U Receptor 1 (NMUR1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NMUR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Live Cell Imaging (LCI)

Produktdetails anti-NMUR1 Antikörper

Bindungsspezifität: AA 316-331, Extracellular, Loop 3

Verwendungszweck: A Rabbit Polyclonal antibody to NMUR1 (extracellular)

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Human - 12 out of 16 amino acid residues identical, Mouse - 10 out of 16 amino acid residues identical

Produktmerkmale: A rabbit polyclonal antibody to NMUR1 (extracellular)

Aufreinigung: Affinity purified on immobilized antigen.

Immunogen: (C)DRLMWSMVSHWTDGLR, corresponding to amino acid residues 316 - 331 of rat NMUR1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

WB: 1:400-1:500

FC: 2.5 μg per reaction

ICC: The optimal concentration should be determined by the user

IHC: 1:300

IP: The optimal concentration should be determined by the user

Kommentare:

Negative Control: (ABIN7236064)

Blocking Peptide: (ABIN7236064)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Konzentration: 0.8 mg/mL

Buffer: PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Details zu NMUR1

Target: NMUR1 (Neuromedin U Receptor 1 (NMUR1))

Andere Bezeichnung: NMUR1

Hintergrund:

Synonyms: Neuromedin-U Receptor 1, G Protein-Coupled Receptor 66, GPR66

Description: Neuromedin U Receptor 1 (NMUR1) is one of the two receptors for the neuropeptide Neuromedin U (NMU). NMUR1 and the second receptor NMUR2 are members of the G protein coupled receptors (GPCRs) superfamily 1.NMU is a neuropeptide with potent activity on smooth muscles that is widely distributed in the gut and central nervous system. NMU interaction with one of its two receptors- NMU1R or NMU2R, mediates the stimulation of smooth muscles, increase of blood pressure, alteration of ion transport in the gut, control of local blood flow and regulation of adrenocortical function1-2.NMU1R is abundantly expressed in peripheral tissues including lung, GI tract, pancreatic islets, testis, adipose, immune tissues, and dorsal root ganglia2, and due to its diverse functions it is a very appealing drug and research candidate.

Gen-ID: 65276

NCBI Accession: NM_006056

UniProt: Q9JJI5