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SH3TC2 Antikörper (AA 851-950) (Cy5)

This anti-SH3TC2 antibody (ABIN1407880) is a Rabbit Polyclonal antibody detecting SH3TC2 in WB, IF (cc), IF (p). Suitable for Human.
Produktnummer ABIN1407880

Kurzübersicht für SH3TC2 Antikörper (AA 851-950) (Cy5) (ABIN1407880)

Target

Alle SH3TC2 Antikörper anzeigen
SH3TC2 (SH3 Domain and Tetratricopeptide Repeats 2 (SH3TC2))

Reaktivität

  • 21
  • 1
Human

Wirt

  • 21
Kaninchen

Klonalität

  • 21
Polyklonal

Konjugat

  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser SH3TC2 Antikörper ist konjugiert mit Cy5

Applikation

  • 15
  • 12
  • 12
  • 9
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 5
    • 1
    • 1
    AA 851-950

    Homologie

    Human,Mouse,Rat,Cow,Pig,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human SH3TC2

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    SH3TC2 (SH3 Domain and Tetratricopeptide Repeats 2 (SH3TC2))

    Andere Bezeichnung

    SH3TC2

    Hintergrund

    Synonyms: KIAA1985, CMT4C, D430044G18Rik, FLJ13605, MNMN, PP12494, RGD1309038, S3TC2_HUMAN, SH3 domain and tetratricopeptide repeats-containing protein 2, SH3TC2.

    Background: SH3TC2 (SH3 domain and tetratricopeptide repeats 2) is a 1,288 amino acid protein that contains one SH3 domain and eight TPR repeats. The SH3TC2 gene encodes a protein expressed in Schwann cells of peripheral nerves, and localized to the plasma membrane and to the perinuclear endocytic recycling compartment, suggesting a possible function in myelination and/or in regions of axoglial interactions. The SH3TC2 protein is expressed in adult heart, testis, spinal cord, and brain as well as in fetal brain and liver. Mild mononeuropathy of the median nerve (MNMN) is caused by heterozygous mutation in the SH3TC2 gene. Also, Charcot-Marie-Tooth disease type 4C (CMT4C) is a more severe neuropathy caused by homozygous or compound heterozygous mutation in the SH3TC2 gene. Existing as four alternatively spliced isoforms and containing 18 exons, the SH3TC2 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 5q32.

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