LAMa4 Antikörper (AA 901-1000) (HRP)

Produktnummer ABIN1406894

Produktdetails anti-LAMa4 Antikörper (HRP)

Target: LAMa4 (Laminin, alpha 4 (LAMa4))

Bindungsspezifität: AA 901-1000

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LAMa4 Antikörper ist konjugiert mit HRP

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Laminin alpha 4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu LAMa4

Target: LAMa4 (Laminin, alpha 4 (LAMa4))

Andere Bezeichnung: Laminin alpha 4 (LAMa4 Produkte)

Synonyme: si:dkey-119m7.3 antikoerper, si:busm1-189a20.2 antikoerper, CMD1JJ antikoerper, LAMA3 antikoerper, LAMA4*-1 antikoerper, RGD1560062 antikoerper, laminin subunit alpha 4 antikoerper, laminin, alpha 4 antikoerper, LAMA4 antikoerper, lama4 antikoerper, Lama4 antikoerper

Hintergrund:

Synonyms: LAMA3, LAMA4 1, LAMA4, LAMA4_HUMAN, Laminin alpha 4, Laminin alpha 4 chain, Laminin subunit alpha 4 precursor, Laminin subunit alpha-4, Laminin-14 subunit alpha, Laminin-8 subunit alpha, Laminin-9 subunit alpha.

Background: Laminins are essential and abundant structural non-collagenous glyco- proteins localizing to basement membranes. Basement membranes (cell-associated extracellular matrices (ECMs)) are polymers of laminins with stabilizing Type IV collagen networks, Nidogen, and several proteoglycans. Basement membranes are found under epithelial layers, around the endothelium of blood vessels, and surrounding muscle, peripheral nerve, and fat cells. Formation of basement membranes influences cell proliferation, phenotype, migration, gene expression, and tissue architecture. Each laminin is a heterotrimer of a, b, and g chain subunits that undergoes cell-secretion and incorporation into the ECM. Laminins can self-assemble, bind to other matrix macromolecules, and have unique and shared cell interactions mediated by integrins, dystroglycan, and cognate laminin receptors. The human Laminin a-4 gene maps to chromosome 6q21 and is expressed in adult heart, lung, ovary, small and large intestines, liver, and placenta.

Pathways: Brown Fat Cell Differentiation