LAMa4 Antikörper (AA 1-100)

Produktnummer ABIN7268183

Der Kaninchen Polyklonal anti-LAMa4 Antikörper wird verwendet zum Nachweis von LAMa4 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für LAMa4 Antikörper (AA 1-100) (ABIN7268183)

Target: LAMa4 (Laminin, alpha 4 (LAMa4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LAMa4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LAMa4 Antikörper

Bindungsspezifität: AA 1-100

Verwendungszweck: LAMA4 Rabbit pAb

Sequenz: MALSSAWRSV LPLWLLWSAA CSRAASGDDN AFPFDIEGSS AVGRQDPPET SEPRVALGRL PPAAEVQCPC HCHPAGAPAP PRAVPHSSFS LSPPLSSPQC

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LAMA4 (NP_001098678.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu LAMa4

Target: LAMa4 (Laminin, alpha 4 (LAMa4))

Andere Bezeichnung: LAMA4

Hintergrund: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. This gene encodes the alpha chain isoform laminin, alpha 4. The domain structure of alpha 4 is similar to that of alpha 3, both of which resemble truncated versions of alpha 1 and alpha 2, in that approximately 1,200 residues at the N-terminus (domains IV, V and VI) have been lost. Laminin, alpha 4 contains the C-terminal G domain which distinguishes all alpha chains from the beta and gamma chains. The RNA analysis from adult and fetal tissues revealed developmental regulation of expression, Tissue-specific utilization of alternative polyA-signal has been described in literature.,LAMA4,CMD1JJ,LAMA3,LAMA4*-1,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Extracellular Matrix,Neuroscience,LAMA4

Molekulargewicht: 12kDa/201kDa/202kDa

Gen-ID: 3910

UniProt: Q16363

Pathways: Brown Fat Cell Differentiation