Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Bestrophin Antikörper (Cy5.5)

Der Kaninchen Polyklonal Anti-Bestrophin-Antikörper wurde für IF (cc) und IF (p) validiert. Er ist geeignet, Bestrophin in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN1406807

Kurzübersicht für Bestrophin Antikörper (Cy5.5) (ABIN1406807)

Target

Bestrophin (LOC100368263)

Reaktivität

  • 23
  • 20
  • 20
  • 6
  • 1
Human, Maus, Ratte

Wirt

  • 23
Kaninchen

Klonalität

  • 23
Polyklonal

Konjugat

  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Bestrophin Antikörper ist konjugiert mit Cy5.5

Applikation

  • 12
  • 12
  • 11
  • 9
  • 8
  • 7
  • 7
  • 7
  • 3
  • 3
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Kreuzreaktivität

    Human

    Homologie

    Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Bestrophin

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    Bestrophin (LOC100368263)

    Andere Bezeichnung

    Bestrophin

    Hintergrund

    Synonyms: BEST 1, BEST1, BEST-1, BEST, Best macular dystrophy, BEST1, BEST1_HUMAN, Bestrophin 1, Bestrophin-1, Bestrophin1, BMD, mBest1, TU15B, Vitellorm macular dystrophy 2, Vitellorm macular dystrophy, Vitellorm macular dystrophy protein 2, VMD 2, VMD2.

    Background: Best vitelliform macular dystrophy, known as Best disease, is an early-onset autosomal dominant condition in which accumulation of lipofuscin-like material within and beneath the RPE leads to progressive loss of central vision. Best disease is frequently a reflection of mutations in the Bestrophin gene, which encodes a protein containing four putative transmembrane domains and localizes to the basolateral plasma membrane of RPE cells. Human Bestrophin forms oligomeric chloride channels that are sensitive to intracellular calcium. Missense mutations at the Bestrophin locus reduces or abolishes Bestrophin protein mediated membrane current. Bestrophin Bestrophin 2,Bestrophin 3, and Bestrophin 4 are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels.

    Gen-ID

    5068
Sie sind hier:
Chat with us!