SLURP1 Antikörper (AbBy Fluor® 488)

Produktnummer ABIN1405432

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SLURP1 in WB und IF (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SLURP1 Antikörper (AbBy Fluor® 488) (ABIN1405432)

Target: SLURP1 (Secreted LY6/PLAUR Domain Containing 1 (SLURP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLURP1 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-SLURP1 Antikörper (AbBy Fluor® 488)

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLURP1/ANUP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SLURP1

Target: SLURP1 (Secreted LY6/PLAUR Domain Containing 1 (SLURP1))

Andere Bezeichnung: ANUP

Hintergrund:

Synonyms: Anti neoplastic urinary protein, ANUP, ARS, ARS component B, ARScomponent B 81/S, ArsB, LY6LS, Lymphocyte antigen 6 like secreted, MDM, Results in cobblestone changes in the skin of the palm, Secreted Ly 6/uPAR related protein 1, Secreted LY6/PLAUR domain containing 1, Secreted Ly6/uPAR related protein 1, SLURP-1, SLURP1, SLUR1_HUMAN.

Background: SLURP1, also known as MDM, ARS, ANUP (anti-neoplastic urinary protein), LY6LS or ArsB (ARS component B), is a 103 amino acid secreted protein that exists as a homodimer possessing antitumor activity. Found in esophagus, stomach, exocervix, gums, urine, sweat, saliva, plasma and tears, SLURP1 is most highly expressed in the acrosyringium of the granular layer of skin, where it helps maintain the structure of the keratinocyte layers of the skin. Also considered a marker for late skin differentiation, SLURP1 contains one UPAR/Ly6 domain and is the cause of an autosomal recessive disorder of the skin known as Mal de Meleda (MDM). MDM Is characterized by nail abnormalities, keratotic skin lesions, transgressive palmoplantar keratoderma (PPK), perioral erythema and may sometimes include hyperhidrosis.

Gen-ID: 57152