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PARP16 Antikörper (AA 120-170) (Biotin)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PARP16 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN1403713

Kurzübersicht für PARP16 Antikörper (AA 120-170) (Biotin) (ABIN1403713)

Target

Alle PARP16 Antikörper anzeigen
PARP16 (Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))

Reaktivität

  • 30
  • 19
  • 19
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 1
Human, Maus, Ratte

Wirt

  • 28
  • 2
Kaninchen

Klonalität

  • 29
  • 1
Polyklonal

Konjugat

  • 12
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PARP16 Antikörper ist konjugiert mit Biotin

Applikation

  • 28
  • 13
  • 10
  • 10
  • 8
  • 4
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 14
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 120-170

    Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human PARP16

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    IHC-P 1:200-400

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    PARP16 (Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))

    Andere Bezeichnung

    PARP16

    Hintergrund

    Synonyms: C15orf30, Chromosome 15 open reading frame 30, EC 2.4.2.30, FLJ25281, PAR16_HUMAN, PARP 16, PARP-16, Parp16, Poly ADP ribose polymerase family member 16, Poly [ADP ribose] polymerase 16, Poly [ADP-ribose] polymerase 16.

    Background: Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors, a process that, when repeated multiple times, leads to the formation of poly(ADPribose) chains on the protein. The presence of these chains alters the function of the target protein and promotes cell survival. PARP proteins are implicated in a variety of diseases, including cancer, neurodegenerative and inflammatory disorders. PARP-16 is a 322 amino acid poly (ADP-ribose) polymerase protein localized to the membrane. Expressed as three isoforms produced by alternative splicing, PARP-16 contains one PARP catalytic domain.

    Gen-ID

    54956

    UniProt

    Q8N5Y8
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