PARP16 Antikörper (AA 120-170) (AbBy Fluor® 350)
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- Target Alle PARP16 Antikörper anzeigen
- PARP16 (Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))
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Bindungsspezifität
- AA 120-170
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PARP16 Antikörper ist konjugiert mit AbBy Fluor® 350
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Applikation
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PARP16
- Isotyp
- IgG
- Top Product
- Discover our top product PARP16 Primärantikörper
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- Applikationshinweise
- IF(IHC-P) 1:50-200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- PARP16 (Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))
- Andere Bezeichnung
- PARP16 (PARP16 Produkte)
- Synonyme
- PARP16 antikoerper, zgc:77744 antikoerper, ARTD15 antikoerper, C15orf30 antikoerper, pART15 antikoerper, BC055447 antikoerper, C79952 antikoerper, PARP-16 antikoerper, LRRGT00109 antikoerper, RGD1306243 antikoerper, poly(ADP-ribose) polymerase family member 16 antikoerper, poly(ADP-ribose) polymerase family member 16 L homeolog antikoerper, poly (ADP-ribose) polymerase family, member 16 antikoerper, PARP16 antikoerper, parp16.L antikoerper, parp16 antikoerper, Parp16 antikoerper
- Hintergrund
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Synonyms: C15orf30, Chromosome 15 open reading frame 30, EC 2.4.2.30, FLJ25281, PAR16_HUMAN, PARP 16, PARP-16, Parp16, Poly ADP ribose polymerase family member 16, Poly [ADP ribose] polymerase 16, Poly [ADP-ribose] polymerase 16.
Background: Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors, a process that, when repeated multiple times, leads to the formation of poly(ADPribose) chains on the protein. The presence of these chains alters the function of the target protein and promotes cell survival. PARP proteins are implicated in a variety of diseases, including cancer, neurodegenerative and inflammatory disorders. PARP-16 is a 322 amino acid poly (ADP-ribose) polymerase protein localized to the membrane. Expressed as three isoforms produced by alternative splicing, PARP-16 contains one PARP catalytic domain.
- Gen-ID
- 54956
- UniProt
- Q8N5Y8
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