TSPEAR Antikörper (AbBy Fluor® 350)

Produktnummer ABIN1403499

Produktdetails anti-TSPEAR Antikörper (AbBy Fluor® 350)

Target: TSPEAR (Thrombospondin-Type Laminin G Domain and EAR Repeats (TSPEAR))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSPEAR Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TSPEAR/C21orf9

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TSPEAR

Target: TSPEAR (Thrombospondin-Type Laminin G Domain and EAR Repeats (TSPEAR))

Andere Bezeichnung: TSPEAR (TSPEAR Produkte)

Hintergrund:

Synonyms: C21orf14, C21orf38, C21orf7, Chromosome 21 open reading frame 38, Chromosome 21 open reading frame 91, Early undferentiated retina and lens, EURL, Protein EURL homolog, YG81, TSEAR_HUMAN.

Background: TSPEAR, also known as C21orf9, is a 669 amino acid secreted protein. Expressed as two isoforms produced by alternative splicing, TSPEAR contains one Thrombospondin N-terminal domain and seven EAR (epilepsy-associated repeat) domains. EAR domains are found in several proteins, including TSPEAR, encoded by genes that map within chromosome regions associated with seizure disorders. It is thought that the EAR domain plays a role in the pathogenesis of epilepsy by either binding to an unknown epileptic ligand or interfering with axon synaptogenesis.

Pathways: Sensory Perception of Sound