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MARCH9 Antikörper (AbBy Fluor® 555)

Der Kaninchen Polyklonal Anti-MARCH9-Antikörper wurde für WB und IF (p) validiert. Er ist geeignet, MARCH9 in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN1402175

Kurzübersicht für MARCH9 Antikörper (AbBy Fluor® 555) (ABIN1402175)

Target

Alle MARCH9 Antikörper anzeigen
MARCH9 (Membrane-Associated Ring Finger (C3HC4) 9 (MARCH9))

Reaktivität

  • 41
  • 29
  • 20
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
Human, Maus, Ratte

Wirt

  • 38
  • 2
Kaninchen

Klonalität

  • 39
  • 2
Polyklonal

Konjugat

  • 13
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MARCH9 Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation

  • 34
  • 12
  • 11
  • 3
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human MARCH9

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    MARCH9 (Membrane-Associated Ring Finger (C3HC4) 9 (MARCH9))

    Andere Bezeichnung

    MARCH9

    Hintergrund

    Synonyms: E3 ubiquitin protein ligase MARCH9, MARCH IX, Membrane associated RING CH protein IX, membrane associated ring finger C3HC4 9, Membrane associated RING finger protein 9, RING finger protein 179, RNF179, MARH9_HUMAN.

    Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). MARCH9 (membrane-associated ring finger (C3HC4) 9), also known as RNF179, is a 346 amino acid multi-pass membrane protein that localizes to the golgi apparatus and contains one RING-CH-type zinc finger. Expressed ubiquitously, MARCH9 exists as a homodimer and functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and is thought to promote the degradation of target proteins, such as CD4 and MHC-I. Multiple isoforms of MARCH9 exist due to alternative splicing events.

    Gen-ID

    92979
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