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MARCH9 Antikörper

MARCH9 Reaktivität: Human, Maus, Ratte WB, IF (p), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1387038
  • Target Alle MARCH9 Antikörper anzeigen
    MARCH9 (Membrane-Associated Ring Finger (C3HC4) 9 (MARCH9))
    Reaktivität
    • 41
    • 24
    • 21
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 38
    • 2
    Kaninchen
    Klonalität
    • 39
    • 2
    Polyklonal
    Konjugat
    • 12
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MARCH9 Antikörper ist unkonjugiert
    Applikation
    • 40
    • 16
    • 12
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MARCH9
    Isotyp
    IgG
    Top Product
    Discover our top product MARCH9 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    MARCH9 (Membrane-Associated Ring Finger (C3HC4) 9 (MARCH9))
    Andere Bezeichnung
    MARCH9 (MARCH9 Produkte)
    Synonyme
    Rnf179 antikoerper, March-IX antikoerper, MARCH-IX antikoerper, RNF179 antikoerper, AI608492 antikoerper, BC019560 antikoerper, membrane associated ring-CH-type finger 9 antikoerper, membrane associated ring-CH-type finger 9 S homeolog antikoerper, membrane-associated ring finger (C3HC4) 9 antikoerper, March9 antikoerper, march9.S antikoerper, MARCH9 antikoerper, march9 antikoerper
    Hintergrund

    Synonyms: E3 ubiquitin protein ligase MARCH9, MARCH IX, Membrane associated RING CH protein IX, membrane associated ring finger C3HC4 9, Membrane associated RING finger protein 9, RING finger protein 179, RNF179, MARH9_HUMAN.

    Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). MARCH9 (membrane-associated ring finger (C3HC4) 9), also known as RNF179, is a 346 amino acid multi-pass membrane protein that localizes to the golgi apparatus and contains one RING-CH-type zinc finger. Expressed ubiquitously, MARCH9 exists as a homodimer and functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and is thought to promote the degradation of target proteins, such as CD4 and MHC-I. Multiple isoforms of MARCH9 exist due to alternative splicing events.

    Gen-ID
    92979
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