MARCH7 Antikörper (AA 65-115) (AbBy Fluor® 647)

Produktnummer ABIN1402164

Dieses Anti-MARCH7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MARCH7 in WB und IF (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für MARCH7 Antikörper (AA 65-115) (AbBy Fluor® 647) (ABIN1402164)

Target: MARCH7 (Membrane-Associated Ring Finger (C3HC4) 7, E3 Ubiquitin Protein Ligase (MARCH7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MARCH7 Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-MARCH7 Antikörper (AbBy Fluor® 647)

Bindungsspezifität: AA 65-115

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MARCH7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu MARCH7

Target: MARCH7 (Membrane-Associated Ring Finger (C3HC4) 7, E3 Ubiquitin Protein Ligase (MARCH7))

Andere Bezeichnung: MARCH7

Hintergrund:

Synonyms: AXO, AXOT, Axotrophin, E3 ubiquitin-protein ligase MARCH7, MARCH VII, MARCH-VII, March7, MARH7_HUMAN, Membrane associated RING CH protein VII, Membrane associated ring finger C3HC4 7 E3 ubiquitin protein ligase, membrane associated ring finger C3HC4 7, Membrane associated RING finger protein 7, Membrane-associated RING finger protein 7, Membrane-associated RING-CH protein VII, RING finger protein 177, RNF177.

Background: Axotrophin is a stem cell gene that encodes a protein which is involved in T lymphocyte regulation (especially in regulating the proliferation) and leukemia inhibitory factor (LIF) release. LIF is a neuropoietic cytokine that is important for stem cell regulation and thymocyte stimulation. Both Axotrophin and LIF are linked to transplantation intolerance. Axotrophin is also involved in corpus callosum differentiation and may play a role in glial cell line-derived neurotrophic factor (GDNF)-dependent sensory neuron survival in the substantia gelatinosa of the adult spinal cord. Axotrophin is primarily expressed in the hippocampus, cortex, purkinje and granule cells of the cerebellum.

Gen-ID: 64844

UniProt: Q9H992