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RNF216 Antikörper (AbBy Fluor® 488)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RNF216 in IF (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN1401142

Kurzübersicht für RNF216 Antikörper (AbBy Fluor® 488) (ABIN1401142)

Target

Alle RNF216 Antikörper anzeigen
RNF216 (Ring Finger Protein 216 (RNF216))

Reaktivität

  • 38
  • 31
  • 19
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 39
Kaninchen

Klonalität

  • 39
Polyklonal

Konjugat

  • 21
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser RNF216 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation

  • 18
  • 12
  • 10
  • 9
  • 8
  • 7
  • 2
  • 1
  • 1
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human TRIAD3

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    RNF216 (Ring Finger Protein 216 (RNF216))

    Andere Bezeichnung

    TRIAD3

    Hintergrund

    Synonyms: E3 ubiquitin ligase TRIAD3, ring finger protein 216, RNF216, Triad domain-containing protein 3, U7I1, UBCE7IP1, Ubiquitin conjugating enzyme 7 interacting protein 1, UiP83, ZIN, Zinc finger protein inhibiting NF kappa B, RN216_HUMAN.

    Background: The TRIAD3 gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known.

    Gen-ID

    54476
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