ZNRF3 Antikörper (AA 120-165) (Biotin)
Kurzübersicht für ZNRF3 Antikörper (AA 120-165) (Biotin) (ABIN1401073)
Target
Alle ZNRF3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 120-165
-
Kreuzreaktivität
- Human, Maus, Ratte
-
Aufreinigung
- Purified by Protein A.
-
Immunogen
- KLH conjugated synthetic peptide derived from human ZNRF3
-
Isotyp
- IgG
-
-
anti-Zinc and Ring Finger Protein 3 (ZNRF3) (AA 56-219) antibody
ZNRF3 Reaktivität: Human ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Zinc and Ring Finger Protein 3 (ZNRF3) (AA 120-165) antibodyZNRF3 Reaktivität: Human, Maus, Ratte IF (p), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
-
-
Applikationshinweise
- IHC-P 1:200-400
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 μg/μL
-
Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C for 12 months.
-
Haltbarkeit
- 12 months
-
-
- ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))
-
Andere Bezeichnung
- ZNRF3
-
Hintergrund
-
Synonyms: RNF203, BK747E2.3, E3 ubiquitin-protein ligase ZNRF3, RING finger protein 203, Zinc/RING finger protein 3, ZNRF3, KIAA1133
Background: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
-
Gen-ID
- 84133
-
UniProt
- Q9ULT6
-
Pathways
- WNT Signalweg
Target
-
