CDK5RAP1 Antikörper (FITC)

Produktnummer ABIN1400696

Der Kaninchen Polyklonal Anti-CDK5RAP1-Antikörper wurde für WB und IF (p) validiert. Er ist geeignet, CDK5RAP1 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für CDK5RAP1 Antikörper (FITC) (ABIN1400696)

Target: CDK5RAP1 (CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK5RAP1 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CDK5RAP1 Antikörper (FITC)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CDK5RAP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CDK5RAP1

Target: CDK5RAP1 (CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1))

Andere Bezeichnung: CDK5RAP1

Hintergrund:

Synonyms: CDK5 activator binding protein C42 like, CDK5 regulatory subunit associated protein 1, CDK5RAP1.3, CDK5RAP1.4, CGI 05, HSPC167, C20orf34 antibody C42, CDK5 activator binding protein C42, CK5P1_HUMAN.

Background: Cyclin dependent kinase 5 (Cdk5) is a key regulator of cell cycle progression in neuronal differentiation that physically associates with and is activated by the neuron-specific protein p35. CDK5RAP1 (Cdk5 regulatory subunit-associated protein 1), also known as Cdk5 activator-binding protein C42, is a 601 amino acid protein that specifically inhibits Cdk5 activation by p35 through formation of a dimer that inhibits kinase activity. CDK5RAP1 contains one TRAM domain, which is thought to bind tRNA and deliver the RNA-modifying enzymatic domain to its target. There are 4 named isoforms of CDK5RAP1 that are produced as a result of alternative splicing events and are expressed at high levels in heart and skeletal muscle.

Gen-ID: 51654